Anti-beta Actin antibody [SP124] - Cytoskeleton Marker,Abcam,AB115777
What is this antibody validated in? Anti-beta Actin antibody [SP124] - Cytoskeleton Marker (ab115777) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of beta Actin? Anti-beta Actin [SP124] - Cytoskeleton Marker (ab115777) specifically detects a band for beta Actin (UniProt: P60709) at a molecular weight of 42kDa. Collaboration Anti-beta Actin [SP124] - Cytoskeleton Marker (ab115777) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). Trusted by the scientific community Anti-beta Actin [SP124] - Cytoskeleton Marker (ab115777) was first used in a scientific publication in 2011 and has been cited over 140 times in peer-reviewed journals. Other related products We have a range of other formats of antibody clone [SP124] also available for your convenience: ab115777, Carrier free - ab242387 , Alexa Fluor® 488 - ab267526 , ab279418, ab317794 , Carrier free - ab317804 What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
IHC-P, Flow Cyt (Intra), WB, ICC/IF
Platform ID
BAB786667949
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed : 25255767, PubMed : 29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed : 29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed : 29925947). Plays a role in the assembly of the gamma-tubulin ring complex (gTuRC), which regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments (PubMed : 39321809, PubMed : 38609661). Part of the ACTR1A/ACTB filament around which the dynactin complex is built (By similarity). The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). See full target information ACTB
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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