Anti-beta Glucuronidase (GUS) antibody - Aminoterminal end,Abcam,AB50148

Target data Displays beta-glucuronidase activity with the artificial substrate p-nitrophenyl-beta-D-glucuronide (PNPG) and with 4-methylumbelliferyl-glucuronide (PubMed : 21051639, PubMed : 23690068, PubMed : 26364932, PubMed : 3105604, PubMed : 33664385). Is likely capable of scavenging glucuronate from a range of chemically distinct xenobiotic and endobiotic glucuronides present in the gastrointestinal (GI) tract, to be able to utilize these diverse sources of carbon. As part of the GI microbiome, this enzyme is able to reactivate glucuronide drug conjugates, such reactivated compounds can significantly damage the GI tract (PubMed : 26364932). See full target information uidA