Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker,Abcam,AB52623
Product Specifications Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB, mIHC in human, mouse, rat samples. Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) specifically detects beta III Tubulin (UniProt ID: Q13509; Molecular weight: 50kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) has been confirmed by testing in knockout samples. Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) has been cited over 55 times in peer reviewed journals and is trusted by the scientific community. Anti-beta III Tubulin antibody [EP1569Y] - Neuronal Marker (ab52623) has 6 independent reviews from customers. Related Products Antibody clone EP1569Y is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 647, Biotin, Alexa Fluor® 594, Alexa Fluor® 555, APC, FITC, PE, Alexa Fluor® 488 ( ab190574 , ab190575 , ab195903 , ab201740 , ab202519 , ab224977 , ab224978 , ab224979 , ab283728 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
Flow Cyt (Intra), IHC-P, mIHC, ICC/IF, WB
Platform ID
BAB787667469
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed : 34996871, PubMed : 38305685, PubMed : 38609661). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed : 34996871, PubMed : 38305685, PubMed : 38609661). Below the cap, alpha-beta tubulin heterodimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed : 34996871, PubMed : 38609661). TUBB3 plays a critical role in proper axon guidance and maintenance (PubMed : 20074521). Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed : 28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed : 28483977). See full target information TUBB3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
- Products>Trial Size Antibodies
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