Anti-beta III Tubulin antibody - Neuronal Marker,Abcam,AB41489
What is this antibody validated in? Anti-beta III Tubulin antibody (ab41489) is a chicken polyclonal antibody and is validated for use in Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse samples. Trusted by the scientific community Anti-beta III Tubulin (ab41489) was first used in a scientific publication in 2006 and has been cited over 60 times in peer-reviewed journals. Reviewed by scientists Anti-beta III Tubulin (ab41489) has over 5 independent reviews from customers.
Host
Chicken
Reactivity
Mouse
Application
ICC/IF
Platform ID
BAB287717445
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed : 34996871). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed : 34996871). Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed : 34996871). TUBB3 plays a critical role in proper axon guidance and maintenance (PubMed : 20074521). Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed : 28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed : 28483977). See full target information TUBB3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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