Anti-beta III Tubulin antibody [TU-20] - Neuronal Marker,Abcam,AB7751

What is this antibody validated in? Anti-beta III Tubulin antibody [TU-20] - Neuronal Marker (ab7751) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. Trusted by the scientific community Anti-beta III Tubulin [TU-20] - Neuronal Marker (ab7751) was first used in a scientific publication in 2002 and has been cited over 190 times in peer-reviewed journals. Reviewed by scientists Anti-beta III Tubulin [TU-20] - Neuronal Marker (ab7751) has over 20 independent reviews from customers. Other related products We have a range of other formats of antibody clone [TU-20] also available for your convenience: ab7751, FITC - ab25770

Host

Mouse

Reactivity

Mouse, Human

Application

IHC-P, Flow Cyt (Intra), ICC/IF, WB

Platform ID

BAB600223692

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-beta III Tubulin antibody [TU-20] - Neuronal Marker
Cat. No.AB7751
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationIHC-P, Flow Cyt (Intra), ICC/IF, WB
ClonalityMonoclonal
Clone NumberTU-20
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TUBB3 aa 400-450 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed : 34996871, PubMed : 38305685, PubMed : 38609661). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed : 34996871, PubMed : 38305685, PubMed : 38609661). Below the cap, alpha-beta tubulin heterodimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed : 34996871, PubMed : 38609661). TUBB3 plays a critical role in proper axon guidance and maintenance (PubMed : 20074521). Binding of NTN1/Netrin-1 to its receptor UNC5C might cause dissociation of UNC5C from polymerized TUBB3 in microtubules and thereby lead to increased microtubule dynamics and axon repulsion (PubMed : 28483977). Plays a role in dorsal root ganglion axon projection towards the spinal cord (PubMed : 28483977). See full target information TUBB3

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.