Anti-beta Synuclein antibody [6A10],Abcam,AB277630
Host
Mouse
Reactivity
Mouse, Rat, Cow
Application
WB, IHC
Platform ID
BAB975311150
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-beta Synuclein antibody [6A10]
Cat. No.AB277630
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Cow
ApplicationWB, IHC
ClonalityMonoclonal
Clone Number6A10
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human SNCB aa 100 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.03% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. See full target information SNCB
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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