Anti-beta Synuclein antibody,Abcam,AB6165
Host
Rabbit
Reactivity
Human
Application
IHC-P
Platform ID
BAB287817397
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-beta Synuclein antibody
Cat. No.AB6165
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human SNCB aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 - 7.4
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease. See full target information SNCB
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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