Anti-c-Fos antibody - BSA free,Abcam,AB190289
Anti-c-Fos antibody - BSA free (ab190289) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-FrFl, IHC-P and WB. Anti-c-Fos antibody - BSA free (ab190289) was first used in a scientific publication in 2015 and has been cited over 216 times in peer reviewed journals. It's performance in IHC in mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-c-Fos antibody - BSA free (ab190289) has high sensitivity and specificity. Anti-c-Fos antibody - BSA free (ab190289) has 8 independent reviews from customers. Anti-c-Fos antibody - BSA free (ab190289) specifically detects c-Fos (UniProt ID: P01100; Molecular weight: 41kDa) and is sold in 100 µL selling sizes. c-Fos is an immediate-early gene widely used in neuro research for its role as a marker of neuronal activation. It is rapidly expressed in response to various stimuli, making it an excellent indicator of neuronal activity and functional mapping. Researchers use c-Fos to study brain activity patterns, synaptic plasticity and the effects of drugs or other interventions on the central nervous system, making it essential for understanding dynamic changes in brain function.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, ICC/IF, IHC-FrFl, IHC-P
Platform ID
BAB545838545
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum. See full target information FOS
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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