Anti-eIF4A1 antibody [EPR14505(B)] - N-terminal,Abcam,AB180506

Name: Anti-eIF4A1 antibody [EPR14505(B)] - N-terminal,Abcam,AB180506
Brand: Buy Antibody
SKU: BAB353285957

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

Flow Cyt (Intra), ICC/IF, WB

Platform ID

BAB353285957

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications

Scientific Background

Specifications

NameAnti-eIF4A1 antibody [EPR14505(B)] - N-terminal

Cat. No.AB180506

HostRabbit

IsotypeIgG

ReactivityHuman

ApplicationFlow Cyt (Intra), ICC/IF, WB

ClonalityMonoclonal

Clone NumberEPR14505(B)

ImmunogenThe exact immunogen used to generate this antibody is proprietary information.

Appearance/FormLiquid

ShippingBlue Ice

FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Storage-20°C

Regulatory StatusResearch Use Only

Scientific Background

Target data ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome (PubMed : 20156963). In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. As a result, promotes cell proliferation and growth (PubMed : 20156963). See full target information EIF4A1

Category Paths

Products>Primary Antibodies>Monoclonal Antibodies

Products>Primary Antibodies>Western Blot Antibodies

Products>Primary Antibodies>Recombinant Antibodies

Request a product

Please provide the required information below so that we can quickly source your products.