Anti-eIF4B antibody,Abcam,AB186856

Host

Rabbit

Reactivity

Human

Application

ICC/IF, WB, IHC-P

Platform ID

BAB040879662

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-eIF4B antibody
Cat. No.AB186856
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration0.27 - 1.11 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human EIF4B aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. See full target information EIF4B

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