Anti-eIF4B (phospho S422) antibody,Abcam,AB59300

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB228423391

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-eIF4B (phospho S422) antibody
Cat. No.AB59300
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Eukaryotic translation initiation factor 4B phospho S422 aa 350-450. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F. See full target information Eukaryotic translation initiation factor 4B phospho S422

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