Anti-eNOS antibody,Abcam,AB5589

What is this antibody validated in? Anti-eNOS antibody (ab5589) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. Trusted by the scientific community Anti-eNOS (ab5589) was first used in a scientific publication in 2003 and has been cited over 120 times in peer-reviewed journals. Reviewed by scientists Anti-eNOS (ab5589) has over 5 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P

Platform ID

BAB980197539

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-eNOS antibody
Cat. No.AB5589
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human NOS3 aa 1150-1200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed : 1378832). NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.. Isoform eNOS13C. Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1. See full target information NOS3

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