Anti-eNOS antibody [M221],Abcam,AB76198
What is this antibody validated in? Anti-eNOS antibody [M221] (ab76198) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse samples. What is the molecular weight of eNOS? Anti-eNOS [M221] (ab76198) specifically detects a band for eNOS (UniProt: P70313) at a molecular weight of 133kDa. Trusted by the scientific community Anti-eNOS [M221] (ab76198) was first used in a scientific publication in 2009 and has been cited over 170 times in peer-reviewed journals. Reviewed by scientists Anti-eNOS [M221] (ab76198) has over 10 independent reviews from customers.
Host
Mouse
Reactivity
Mouse, Human
Application
IHC-P, ICC/IF, WB
Platform ID
BAB417766256
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-eNOS antibody [M221]
Cat. No.AB76198
HostMouse
IsotypeIgG1
ReactivityMouse, Human
ApplicationIHC-P, ICC/IF, WB
ClonalityMonoclonal
Clone NumberM221
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Mouse Nos3 aa 1000 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed : 1378832). NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.. Isoform eNOS13C. Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1. See full target information NOS3
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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