Anti-eNOS (phospho S1177) antibody [EPR20991],Abcam,AB215717

What is this antibody validated in? Anti-eNOS (phospho S1177) antibody [EPR20991] (ab215717) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Dot Blot in Human, Mouse samples. What is the molecular weight of eNOS? Anti-eNOS (phospho S1177) [EPR20991] (ab215717) specifically detects a band for eNOS (UniProt: P29474) at a molecular weight of 133kDa. Trusted by the scientific community Anti-eNOS (phospho S1177) [EPR20991] (ab215717) was first used in a scientific publication in 2018 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR20991] also available for your convenience: ab215717, Carrier free - ab230158 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Human

Application

Dot, IP, WB

Platform ID

BAB667791244

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-eNOS (phospho S1177) antibody [EPR20991]
Cat. No.AB215717
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationDot, IP, WB
ClonalityMonoclonal
Clone NumberEPR20991
Concentration0.519 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway (PubMed : 1378832). NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.. Isoform eNOS13C. Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1. See full target information NOS3 phospho S1177

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