Anti-gamma H2A.X (phospho S139) antibody [9F3],Abcam,AB26350
Anti-gamma H2A.X (phospho S139) antibody [9F3] (ab26350) is a House Mouse Monoclonal antibody and is validated for use in Flow Cyt, IHC-P, WB. Anti-gamma H2A.X (phospho S139) antibody [9F3] (ab26350) has been cited over 343 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-gamma H2A.X (phospho S139) antibody [9F3] (ab26350) has high sensitivity and specificity. Anti-gamma H2A.X (phospho S139) antibody [9F3] (ab26350) has 30 independent reviews from customers. Anti-gamma H2A.X (phospho S139) antibody [9F3] (ab26350) specifically detects gamma H2A.X Phospho-S139 (UniProt ID: P16104; Molecular weight: 15kDa) and is sold in 100 ug selling sizes. This product was changed from ascites to tissue culture supernatant on 22nd May 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Host
Mouse
Reactivity
Mouse, Rat, Human, Chinese hamster
Application
IHC-P, Flow Cyt, WB
Platform ID
BAB876524797
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data The protein expressed by the H2AX gene is a variant histone H2A that replaces conventional H2A in certain nucleosomes, which are responsible for wrapping and compacting DNA into chromatin. This compaction limits DNA accessibility to cellular machineries that require DNA as a template, placing histones at the center of transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is controlled through a complex array of post-translational histone modifications, known as the histone code, and nucleosome remodeling. The H2AX protein is essential for the checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for the efficient repair of DNA double strand breaks (DSBs), particularly when it undergoes C-terminal phosphorylation. This supplementary information is collated from multiple sources and compiled automatically. See full target information H2AX phospho S139
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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