Anti-gamma Tubulin antibody - Centrosome Marker,Abcam,AB11321

Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Host

Rabbit

Reactivity

Mouse, Rat, Dog, Human, Chinese hamster

Application

WB, ICC

Platform ID

BAB689180972

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-gamma Tubulin antibody - Centrosome Marker
Cat. No.AB11321
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Dog, Human, Chinese hamster
ApplicationWB, ICC
ClonalityPolyclonal
Concentration8 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Xenopus laevis Tubulin gamma-1 chain aa 400 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed : 38305685). Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed : 38305685). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed : 38305685). See full target information TUBG2 Additional targets TUBG2

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