Anti-gamma Tubulin antibody [TU-30] - Centrosome Marker,Abcam,AB27074

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), WB, ICC/IF

Platform ID

BAB189230948

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-gamma Tubulin antibody [TU-30] - Centrosome Marker
Cat. No.AB27074
HostMouse
IsotypeIgG1
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), WB, ICC/IF
ClonalityMonoclonal
Clone NumberTU-30
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human TUBG1 aa 400-450 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.097% Sodium azide
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tubulin is the major constituent of microtubules, protein filaments consisting of alpha- and beta-tubulin heterodimers (PubMed : 38305685). Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed : 38305685). The gTuRC regulates the minus-end nucleation of alpha-beta tubulin heterodimers that grow into microtubule protafilaments, a critical step in centrosome duplication and spindle formation (PubMed : 38305685). See full target information TUBG2

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