Anti-hnRNP A1 antibody [9H10],Abcam,AB5832
What is this antibody validated in? Anti-hnRNP A1 antibody [9H10] (ab5832) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA in Human, Mouse samples. What is the molecular weight of hnRNP A1? Anti-hnRNP A1 [9H10] (ab5832) specifically detects a band for hnRNP A1 (UniProt: P09651) at a molecular weight of 38kDa. Trusted by the scientific community Anti-hnRNP A1 [9H10] (ab5832) was first used in a scientific publication in 2003 and has been cited over 50 times in peer-reviewed journals.
Host
Mouse
Reactivity
Human, Mouse
Application
IHC-P, Flow Cyt, ELISA, ICC/IF, IP, WB
Platform ID
BAB023376803
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Involved in the packaging of pre-mRNA into hnRNP particles, transport of poly(A) mRNA from the nucleus to the cytoplasm and modulation of splice site selection (PubMed : 17371836). Plays a role in the splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (PubMed : 20010808). Binds to the IRES and thereby inhibits the translation of the apoptosis protease activating factor APAF1 (PubMed : 31498791). May bind to specific miRNA hairpins (PubMed : 28431233).. (Microbial infection) May play a role in HCV RNA replication.. (Microbial infection) Cleavage by Enterovirus 71 protease 3C results in increased translation of apoptosis protease activating factor APAF1, leading to apoptosis. See full target information HNRNPA1
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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