Anti-nkx6.1 antibody [EPR20405],Abcam,AB221549

What is this antibody validated in? Anti-nkx6.1 antibody [EPR20405] (ab221549) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr) in Human, Mouse samples. What is the molecular weight of nkx6.1? Anti-nkx6.1 [EPR20405] (ab221549) specifically detects a band for nkx6.1 (UniProt: P78426) at a molecular weight of 38kDa. Trusted by the scientific community Anti-nkx6.1 [EPR20405] (ab221549) was first used in a scientific publication in 2017 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR20405] also available for your convenience: ab221549, Carrier free - ab240398 , Alexa Fluor® 647 - ab322233 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Human

Application

IHC-Fr, WB, IHC-P

Platform ID

BAB652476070

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-nkx6.1 antibody [EPR20405]
Cat. No.AB221549
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-Fr, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR20405
Concentration0.5935 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity). Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity). See full target information NKX6-1

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