Anti-p57 Kip2 antibody [KIP2/880],Abcam,AB220207

Host

Mouse

Reactivity

Human

Application

IHC-P

Platform ID

BAB537208896

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-p57 Kip2 antibody [KIP2/880]
Cat. No.AB220207
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberKIP2/880
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human CDKN1C.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life. See full target information CDKN1C

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