Anti-p63 antibody [4A4],Abcam,AB735
Please note that clone [BC4A4] and clone [4A4] are identical. This product was changed from ascites to tissue culture supernatant on 14/07/17. The following lots are from ascites and are still in stock as of 14/07/17 – GR323232, GR293168, and GR301030. Lot numbers higher than GR323232 will be from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly. Product Specifications Anti-p63 antibody [4A4] (ab735) is a mouse monoclonal antibody and is validated for use in IHC-P in human samples. Anti-p63 antibody [4A4] (ab735) specifically detects p63 (UniProt ID: Q9H3D4; Molecular weight: 77kDa) and is sold in 250 µL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-p63 antibody [4A4] (ab735) has high sensitivity and specificity. Anti-p63 antibody [4A4] (ab735) has been cited over 153 times in peer reviewed journals and is trusted by the scientific community. Anti-p63 antibody [4A4] (ab735) has 12 independent reviews from customers. Related Products Conjugation-ready, carrier free format available for antibody clone 4A4 - ab256584 .
Host
Mouse
Reactivity
Human
Application
IHC-P
Platform ID
BAB599790107
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter. See full target information TP63
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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