Anti-pan Cadherin antibody [EPR1792Y] - Intercellular Junction Marker,Abcam,AB51034
What is this antibody validated in? Anti-pan Cadherin antibody [EPR1792Y] - Intercellular Junction Marker (ab51034) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of pan Cadherin? Anti-pan Cadherin [EPR1792Y] - Intercellular Junction Marker (ab51034) specifically detects a band for pan Cadherin (UniProt: P19022) at a molecular weight of 100kDa. Trusted by the scientific community Anti-pan Cadherin [EPR1792Y] - Intercellular Junction Marker (ab51034) was first used in a scientific publication in 2007 and has been cited over 20 times in peer-reviewed journals. Reviewed by scientists Anti-pan Cadherin [EPR1792Y] - Intercellular Junction Marker (ab51034) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR1792Y] also available for your convenience: ab51034, Alexa Fluor® 488 - ab195202 , Alexa Fluor® 647 - ab195203 , Carrier free - ab239839 , PE - ab303080 , APC - ab303081 , HRP - ab303082 , Alkaline Phosphatase - ab308963 , Alexa Fluor® 594 - ab310734 , Alexa Fluor® 555 - ab312264 , Alexa Fluor® 568 - ab312753 , Alexa Fluor® 750 - ab321637 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB, Flow Cyt (Intra), ICC/IF, IP, IHC-P
Platform ID
BAB413845610
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell. Cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone : upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (By similarity). Required for proper neurite branching. Required for pre- and postsynaptic organization (By similarity). CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. May promote axon outgrowth and motor fiber repair via DSP-mediated recruitment to outgrowth tips (By similarity). See full target information CDH2
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