Anti-proCNP antibody - C-terminal,Abcam,AB202139

Host

Rabbit

Reactivity

Human

Application

IHC-P

Platform ID

BAB194006126

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-proCNP antibody - C-terminal
Cat. No.AB202139
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration0.6 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human NPPC. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data CNP-22. Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic (PubMed : 1672777). Acts by specifically binding and stimulating NPR2 to produce cGMP (PubMed : 1672777, PubMed : 21098034). Binds the clearance receptor NPR3 (PubMed : 11533490). See full target information NPPC

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