Anti-uPA Receptor/U-PAR antibody [VIM5],Abcam,AB234179

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Platform ID

BAB007750514

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-uPA Receptor/U-PAR antibody [VIM5]
Cat. No.AB234179
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberVIM5
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing PLAUR protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a receptor for urokinase plasminogen activator (PubMed : 15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. See full target information PLAUR

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