Antithrombin III antibody, C-term,Genetex,GTX81758

Host

Rabbit

Reactivity

Human, Mouse

Application

WB ICC/IF IHC-P FCM

Conjugate

Unconjugated

Platform ID

BAB938707579

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameAntithrombin III antibody, C-term
Cat. No.GTX81758
Gene ID (Entrez)462
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P FCM
ClonalityPolyclonal
ConcentrationBatch dependent (Please refer to the vial label for the specific concentration.)
TargetSERPINC1
ImmunogenKLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1.
PuritySaturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS,0.09% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq, Jul 2009]

Synonyms

serpin family C member 1 , AT3 , AT3D , ATIII , ATIII-R2 , ATIII-T1 , ATIII-T2 , THPH7

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