Apolipoprotein E antibody [GT27711],Genetex,GTX635889

Host

Mouse

Reactivity

Human, Mouse, Rat

Application

WB IHC-P IP ELISA Sandwich ELISA

Conjugate

Unconjugated

Platform ID

BAB522040089

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameApolipoprotein E antibody [GT27711]
Cat. No.GTX635889
Gene ID (Entrez)348
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IHC-P IP ELISA Sandwich ELISA
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetAPOE
ImmunogenRecombinant protein encompassing a sequence within the center region of human Apolipoprotein E. The exact sequence is proprietary.
PurityAffinity purified by Protein A.
Appearance/FormLiquid
FormulationPBS, 20% Glycerol,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016]

Synonyms

apolipoprotein E , AD2 , APO-E , ApoE4 , LDLCQ5 , LPG

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