Aurora B (phospho Thr232) antibody,Genetex,GTX85607

Host

Rabbit

Reactivity

Human, Monkey

Application

WB ICC/IF IHC-P Dot ELISA Multiplexing

Conjugate

Unconjugated

Platform ID

BAB950601867

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAurora B (phospho Thr232) antibody
Cat. No.GTX85607
Gene ID (Entrez)9212
HostRabbit
IsotypeIgG
ReactivityHuman, Monkey
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P Dot ELISA Multiplexing
ClonalityPolyclonal
Concentration0.87 mg/ml (Please refer to the vial label for the specific concentration.)
TargetA
ImmunogenSynthetic peptide corresponding to an internal region surrounding T232 of Human Aurora Kinase B protein.
PurityPurified by antigen-affinity chromatography.From serum
Appearance/FormLiquid
Formulation20mM Potassium Phosphate, 150mM NaCl,0.01% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM]

Synonyms

aurora kinase B , AIK2 , AIM-1 , AIM1 , ARK-2 , ARK2 , AurB , IPL1 , PPP1R48 , STK-1 , STK12 , STK5 , aurkb-sv1 , aurkb-sv2

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