Aurora Kinase C (AURKC) Antibody,Abbexa,abx033107
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
Host
Rabbit
Reactivity
Human
Application
ELISA, WB
Conjugate
Unconjugated
Platform ID
BAB696647732
Abbexa
Contact
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Product Specifications
Specifications
NameAurora Kinase C (AURKC) Antibody
Cat. No.abx033107
Accession NumberQ9UQB9
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationELISA, WB
Working DilutionsWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
Molecular WeightCalculated MW: 35.6 kDa
ImmunogenKLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Aurora-C.
PurityPurified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Appearance/FormLiquid
FormulationPBS containing 0.09% sodium azide.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Regulatory StatusResearch Use Only
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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