Avian Influenza A virus H5N1 NA (Neuraminidase) antibody,Genetex,GTX41305

Host

Rabbit

Reactivity

Avian Influenza A virus

Application

ELISA

Conjugate

Unconjugated

Platform ID

BAB214242845

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameAvian Influenza A virus H5N1 NA (Neuraminidase) antibody
Cat. No.GTX41305
HostRabbit
IsotypeIgG
ReactivityAvian Influenza A virus
ConjugationUnconjugated
ApplicationELISA
ClonalityPolyclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
ImmunogenAvian influenza neuraminidase antibody was raised against a synthetic peptide corresponding to 16 amino acids in the middle of the avian influenza neuraminidase protein.Efforts were made to use relatively conserved regions as the antigen.The immunogen is located within amino acids 150 - 200 of Avian Influenza Neuraminidase.
PurityPurified by antigen-affinity chromatography
Appearance/FormLiquid
FormulationPBS,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus.

Synonyms

Influenza A Virus Neuraminidase , Influenza A Virus NA

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