BACE2 antibody,Genetex,GTX28025

This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

AEPLC , ALP56 , ASP1 , ASP21 , BACE2 , BAE2 , CDA13 , CEAP1 , DRAP , betasite APPcleaving enzyme 2 , beta-secretase 2