BAF57 antibody [C3], C-term,Genetex,GTX106345

Host

Rabbit

Reactivity

Human

Application

WB ICC/IF IHC-P

Conjugate

Unconjugated

Platform ID

BAB556157498

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameBAF57 antibody [C3], C-term
Cat. No.GTX106345
Gene ID (Entrez)6605
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityPolyclonal
Concentration1.04 mg/ml (Please refer to the vial label for the specific concentration.)
TargetSMARCE1
ImmunogenCarrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BAF57. The exact sequence is proprietary.
PurityPurified by antigen-affinity chromatography.
Appearance/FormLiquid
Formulation0.1M Tris, 0.1M Glycine, 10% Glycerol,0.01% Thimerosal
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq]

Synonyms

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 , BAF57 , CSS5

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