BAG2 antibody, C-term,Genetex,GTX89538

Host

Goat

Reactivity

Human, Pig

Application

WB

Conjugate

Unconjugated

Platform ID

BAB087558625

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBAG2 antibody, C-term
Cat. No.GTX89538
Gene ID (Entrez)9532
HostGoat
IsotypeIgG
ReactivityHuman, Pig
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBAG2
ImmunogenPeptide with sequence CSKTLQQNAESRFN, from the C Terminus of the protein sequence according to NP_004273.1.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq, Jul 2008]

Synonyms

BCL2 associated athanogene 2 , BAG-2 , dJ417I1.2

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