BATF3 (E3K5H) Rabbit Monoclonal Antibody (BSA and Azide Free)#62132,Cell Signaling Technology (CST),62132

BATF3 (E3K5H) Rabbit Monoclonal Antibody (BSA and Azide Free) recognizes endogenous levels of total human BATF3 protein. This clone exhibits reactivity by western blot in cell lines transfected with a construct expressing Myc/DDK-tagged mouse BATF3 protein.

Host

Rabbit

Reactivity

Human

Platform ID

BAB277744763

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBATF3 (E3K5H) Rabbit Monoclonal Antibody (BSA and Azide Free)#62132
Cat. No.62132
Accession NumberQ9NR55
Gene ID (Entrez)55509
HostRabbit
SensitivityEndogenous
ReactivityHuman
Molecular Weight18
ImmunogenIgG
FormulationThis product is the carrier free version of product #16484. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, pleasecontact us. Optimal dilutions/concentrations should be determined by the end user.BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
StorageStore at -20°C.This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles.A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Regulatory StatusResearch Use Only

Scientific Background

BATF3 (Basic leucine zipper transcriptional factor ATF-like 3, p21SNFT) is a member of the basic leucine zipper family (1,2,5) which dimerizes with Jun proteins and represses activator protein-1 (AP-1) activity (1). BATF3 is required for development of conventional type 1 dendritic cells (cDC1s), which cross-present antigens in the context of MHC class I to naïve CD8+T cells, priming them to become activated cytotoxic CD8+T cells (2-4).Iacobelli, M. et al. (2000)J Immunol165, 860-8.Bower, K.E. et al. (2002)J Biol Chem277, 34967-77.Hildner, K. et al. (2008)Science322, 1097-100.Gutiérrez-Martínez, E. et al. (2015)Front Immunol6, 363.Fu, C. and Jiang, A. (2018)Front Immunol9, 3059.Alternate Names21 kDa small nuclear factor isolated from T-cells; 21-kD small nuclear factor isolated from T cells; B-ATF-3; basic leucine zipper ATF-like transcription factor 3; basic leucine zipper transcription factor, ATF-like 3; Basic leucine zipper transcriptional factor ATF-like 3; BATF3; FLJ36352; FLJ37535; JDP1; Jun dimerization protein 1; Jun dimerization protein p21SNFT; JUNDM1; SNFT

Synonyms

21 kDa small nuclear factor isolated from T-cells; 21-kD small nuclear factor isolated from T cells; B-ATF-3; basic leucine zipper ATF-like transcription factor 3; basic leucine zipper transcription factor, ATF-like 3; Basic leucine zipper transcriptional factor ATF-like 3; BATF3; FLJ36352; FLJ37535; JDP1; Jun dimerization protein 1; Jun dimerization protein p21SNFT; JUNDM1; SNFT

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