BCAT1 (D6D4K) Rabbit Monoclonal Antibody#88785,Cell Signaling Technology (CST),88785

BCAT1 (D6D4K) Rabbit Monoclonal Antibody recognizes endogenous levels of total BCAT1 protein. This antibody does not cross-react with BCAT2 protein.

Host

Rabbit

Reactivity

Human, Mouse

Application

Western Blotting: 1:1000

Platform ID

BAB652832221

Cell Signaling Technology (CST)

Headquarters

3 Trask Lane Danvers, MA 01923

Cell Signaling Technology (CST)

Contact

Tel: 877-616-2355,978-867-2388
Fax: 877-616-2355

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBCAT1 (D6D4K) Rabbit Monoclonal Antibody#88785
Cat. No.88785
Accession NumberP54687
Gene ID (Entrez)54687
HostRabbit
SensitivityEndogenous
ReactivityHuman, Mouse
ApplicationWestern Blotting: 1:1000
Molecular Weight43
ImmunogenIgG
FormulationSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
StorageSupplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
Regulatory StatusResearch Use Only

Scientific Background

BCAT1 and BCAT2 are cytosolic and mitochondrial branched chain aminotransferases, respectively (1,2). Research studies have implicated BCAT1 in distant metastasis in patients with advanced colorectal cancer (3). Disruption of BCAT2 in mice leads to higher levels of plasma branched-chain amino acids, reduced adiposity and body weight, and increased energy expenditure, suggesting its role in regulating insulin sensitivity (4).Bledsoe, R.K. et al. (1997)Biochim Biophys Acta1339, 9-13.Suryawan, A. et al. (1998)Am J Clin Nutr68, 72-81.Yoshikawa, R. et al. (2006)World J Gastroenterol12, 5884-9.She, P. et al. (2007)Cell Metab6, 181-94.Alternate NamesBCAT(c); BCAT1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; DKFZp686E12175; ECA39; MECA39; placental protein 18; PNAS-121; PNAS121; PP18; Protein ECA39

Synonyms

BCAT(c); BCAT1; BCATC; BCT1; branched chain amino acid transaminase 1; branched chain amino-acid transaminase 1, cytosolic; branched chain aminotransferase 1, cytosolic; Branched-chain-amino-acid aminotransferase, cytosolic; DKFZp686E12175; ECA39; MECA39; placental protein 18; PNAS-121; PNAS121; PP18; Protein ECA39

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