BCL6 Rabbit mAb,ABclonal,A22610

Reactivity

Human

Application

FC (intra), ELISA

Conjugate

Unconjugated

Platform ID

BAB113612320

ABclonal

Headquarters

500W Cummings Park, Ste. 6500 Woburn, MA 01801

ABclonal

Contact

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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBCL6 Rabbit mAb
Cat. No.A22610
Accession NumberP41182
Gene ID (Entrez)604
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationFC (intra), ELISA
Working DilutionsFC (intra):1:100 - 1:500 | ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Clone NumberARC57886
Molecular WeightRefer to figures
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
PurityAffinity purification
Appearance/FormLiquid
StorageStore at -20℃. Avoid freeze / thaw cycles.; Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Synonyms

BCL5; LAZ3; BCL6A; ZNF51; ZBTB27; BCL6

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