BCL6 antibody [BCL6/1526],Genetex,GTX34433

Host

Mouse

Reactivity

Human

Application

IHC-P Protein Array

Conjugate

Unconjugated

Platform ID

BAB514255092

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBCL6 antibody [BCL6/1526]
Cat. No.GTX34433
Gene ID (Entrez)604
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationUnconjugated
ApplicationIHC-P Protein Array
ClonalityMonoclonal
Concentration0.2 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBCL6
ImmunogenRecombinant human bcl-6 protein fragment (aa256-389) (Exact sequence is proprietary)
PurityProtein A/G purified
Appearance/FormLiquid
FormulationPBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

Synonyms

BCL5 , BCL6 , BCL6A , Bcell CLL/lymphoma 6 , LAZ3 , ZBTB27 , ZNF51 , BCL6 transcription repressor

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