BLNK Recombinant Antibody,Bioss,bsm-62608r-100ul

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

FCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)

Conjugate

Unconjugated

Platform ID

BAB948111568

Bioss

Headquarters

300 Tradecenter Dr, ste 4610Woburn, Massachusetts 01801 - U.S.A.

Bioss

Contact

Tel: +1.781.569.5821
Fax: +1.781.731.9286

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBLNK Recombinant Antibody
Cat. No.bsm-62608r-100ul
Accession NumberQ8WV28
Gene ID (Entrez)29760
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationFCM, IHC-P, IHC-F, IF(IHC-P), IF(ICC)
Working DilutionsFCM:1:50-100 | IHC-P:IHC-P1:50-200 | IHC-F:IHC-F1:50-200 | IF(IHC-P):IFIHC-P1:50-200 | IF(ICC):IFICC1:100-500
ClonalityRecombinant
ConcentrationLot dependent
PurityPurified by Protein A.
Formulation0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
StorageShipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Scientific Background

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes.

Synonyms

AGM4; BASH; Bca; BLNK; Ly57; Lyw57; SLP65.

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