BMP10 antibody [5L26],Genetex,GTX52564

Host

Mouse

Reactivity

Human

Application

WB Neutralizing /Inhibition

Conjugate

Unconjugated

Platform ID

BAB246527341

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBMP10 antibody [5L26]
Cat. No.GTX52564
Gene ID (Entrez)27302
HostMouse
IsotypeIgG2
ReactivityHuman
ConjugationUnconjugated
ApplicationWB Neutralizing /Inhibition
ClonalityMonoclonal
Concentration500 μg/ml (Please refer to the vial label for the specific concentration.)
TargetBMP10
ImmunogenHuman recombinant BMP-10
PurityProtein G purifiedFrom tissue culture supernatant
Appearance/FormLiquid
FormulationPBS,No preservatives
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]

Synonyms

BMP10 , bone morphogenetic protein 10

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