BMP8 antibody,Genetex,GTX14934

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

WB IP ELISA

Conjugate

Unconjugated

Platform ID

BAB539854063

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Genetex

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBMP8 antibody
Cat. No.GTX14934
Gene ID (Entrez)656
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ConjugationUnconjugated
ApplicationWB IP ELISA
ClonalityPolyclonal
Concentration0.57-0.68 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBMP8B
ImmunogenSynthetic peptide taken within amino acid region 160-200 on human BMP8 protein
PurityPurified by affinity chromatography
Appearance/FormLiquid
FormulationTris/Glycine, 0.5% BSA, 30% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]

Synonyms

bone morphogenetic protein 8b , BMP8 , OP2

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