Bacillus anthracis protective antigen antibody,Genetex,GTX13809
Host
Rabbit
Reactivity
Bacillus anthracis
Application
WB
Conjugate
Unconjugated
Platform ID
BAB913142385
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Specifications
NameBacillus anthracis protective antigen antibody
Cat. No.GTX13809
HostRabbit
IsotypeIgG
ReactivityBacillus anthracis
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
ImmunogenThe antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino acids 186-192 of the Anthrax PA protein (approx. 83 kDa).
PurityUnpurified
Appearance/FormLiquid
FormulationSerum diluted with PBS, 0.05% BSA,0.05% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Anthrax PA (Protective Antigen) and Anthrax LF (Lethal Factor), along with Anthrax EF (Edema Factor), are toxins produced by Bacillus anthracis. All three of the proteins must be present for toxicity to occur. It begins with the binding of PA to its cell-surface receptor, ATR (Anthrax Toxin Receptor), at which point PA is cleaved and the resulting 63 kD carboxyl-terminal fragment binds to LF and EF. LF is a protease that is known to cleave members of the mitogen-activated protein kinase kinase (MAPKK) family.
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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