Bad Antibody (YA6225),MedChemexpress,HY-P86533

Bad Antibody (YA6225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Bad.

Host

Rabbit

Reactivity

Human,Mouse,Rat

Application

WB,IHC-P,ICC/IF,IP,ELISA

Conjugate

Non-conjugated

Platform ID

BAB788849891

Master of Bioactive Molecules

MedChemexpress

Master of Bioactive Molecules

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Contact

Tel: 609-228-6898
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Email:

[email protected]

Product Specifications
Scientific Background
Synonyms

Specifications

NameBad Antibody (YA6225)
Cat. No.HY-P86533
Accession NumberQ92934
Gene ID (Entrez)572
HostRabbit
RRIDAB_3719178
IsotypeIgG
ReactivityHuman,Mouse,Rat
ConjugationNon-conjugated
ApplicationWB,IHC-P,ICC/IF,IP,ELISA
Working DilutionsIHC-P: 1:200-1:1000; WB: 1:1000-1:5000; ICC/IF: 1:200-1:1000; ELISA: 1:5000-1:20000; IP: 1:50-1:200
ClonalityMonoclonal
Clone NumberYA6225
Molecular WeightPredicted band size: 18 kDa; Observed band size: 23 kDa
PurityProtein A
Appearance/FormLiquid
ShippingShipping with blue ice.
FormulationSupplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
StorageStored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

Bad is a protein that promotes cell death. It successfully competes for binding to Bcl-X(L), Bcl-2, and Bcl-W, thereby influencing the heterodimerization levels of these proteins with BAX. Bad can reverse the death repressor activity of Bcl-X(L) but not that of Bcl-2 (By similarity). Additionally, it appears to act as a link between growth factor receptor signaling and apoptotic pathways.

Synonyms

BAD; BBC6; BCL2L8; Bcl2 antagonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-XL/Bcl-2-associated death promoter

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