Bcl-2 antibody [8E12],Genetex,GTX82803
Host
Mouse
Reactivity
Human, Mouse
Application
ICC/IF IHC-P FCM ELISA
Conjugate
Unconjugated
Platform ID
BAB003187878
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameBcl-2 antibody [8E12]
Cat. No.GTX82803
Gene ID (Entrez)596
HostMouse
IsotypeIgG1
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationICC/IF IHC-P FCM ELISA
ClonalityMonoclonal
TargetBCL2
ImmunogenSynthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
PurityUnpurified
Appearance/FormLiquid
FormulationAscites,0.03% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]
Synonyms
BCL2 apoptosis regulator , Bcl-2 , PPP1R50
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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