Bcl-2 antibody [AT1B5],Genetex,GTX57574

Host

Mouse

Reactivity

Human, Mouse

Application

WB ICC/IF FCM

Conjugate

Unconjugated

Platform ID

BAB763469205

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameBcl-2 antibody [AT1B5]
Cat. No.GTX57574
Gene ID (Entrez)596
HostMouse
IsotypeIgG2b
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF FCM
ClonalityMonoclonal
Concentration1 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBCL2
ImmunogenThe clone AT1B5 is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Bcl-4 protein.
PurityProtein G Purified
Appearance/FormLiquid
FormulationPBS, 10% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Synonyms

BCL2 apoptosis regulator , BCL2 , BCL2, apoptosis regulator , Bcl2 , PPP1R50 , Bcl-2

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