Bcl-2 antibody, N-term,Genetex,GTX89719

Host

Goat

Reactivity

Human

Application

WB

Conjugate

Unconjugated

Platform ID

BAB463445699

Genetex

Headquarters

2456 Alton Pkwy Irvine, CA 92606 USA

Contact

Tel: 1-949-553-1900
Fax: 1-949-309-2888

Product Specifications
Scientific Background
Synonyms

Specifications

NameBcl-2 antibody, N-term
Cat. No.GTX89719
Gene ID (Entrez)596
HostGoat
IsotypeIgG
ReactivityHuman
ConjugationUnconjugated
ApplicationWB
ClonalityPolyclonal
Concentration0.50 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBCL2
ImmunogenPeptide with sequence AGRTGYDNREIVMKYC, from the N Terminus of the protein sequence according to NP_000624.2; NP_000648.2.
PurityPurified by ammonium sulphate precipitation followed by antigen affinity chromatography
Appearance/FormLiquid
FormulationTBS, 0.5% BSA,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only

Scientific Background

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Synonyms

BCL2 apoptosis regulator , Bcl-2 , PPP1R50

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