Bcl-XL antibody [4A9],Genetex,GTX84834
Host
Mouse
Reactivity
Human, Mouse
Application
WB ICC/IF IHC-P
Conjugate
Unconjugated
Platform ID
BAB322191005
Genetex
Contact
Tel: 1-949-553-1900
Fax: 1-949-309-2888
Email:
Product Specifications
Scientific Background
Synonyms
Specifications
NameBcl-XL antibody [4A9]
Cat. No.GTX84834
Gene ID (Entrez)598
HostMouse
IsotypeIgG2a
ReactivityHuman, Mouse
ConjugationUnconjugated
ApplicationWB ICC/IF IHC-P
ClonalityMonoclonal
Concentration0.25 mg/ml (Please refer to the vial label for the specific concentration.)
TargetBCL2L1
ImmunogenRecombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
PurityPurified IgG
Appearance/FormLiquid
FormulationPBS, 1% BSA, 50% Glycerol,0.02% Sodium azide
StorageStore as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Regulatory StatusResearch Use Only
Scientific Background
Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Isoform Bcl-X(S) promotes apoptosis.
Synonyms
BCL2 like 1 , BCL-XL/S , BCL2L , BCLX , Bcl-X , PPP1R52
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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