Biotin Anti-CD32B + CD32A antibody [AT10],Abcam,AB30355

Host

Mouse

Reactivity

Human

Application

Flow Cyt

Conjugate

Biotin

Platform ID

BAB476760454

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-CD32B + CD32A antibody [AT10]
Cat. No.AB30355
HostMouse
IsotypeIgG1
ReactivityHuman
ConjugationBiotin
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberAT10
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing FCGR2B protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis. See full target information FCGR2B Additional targets FCGR2A

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