Biotin Anti-CGRP antibody,Abcam,AB47856

Host

Rabbit

Reactivity

Human

Application

IP, RIA, ELISA

Conjugate

Biotin

Platform ID

BAB789566557

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-CGRP antibody
Cat. No.AB47856
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationIP, RIA, ELISA
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed : 1318039, PubMed : 33602864, PubMed : 9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed : 3492492). It also elevates platelet cAMP (PubMed : 1318039). CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex (PubMed : 38603770). See full target information CALCA

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