Biotin Anti-FGF2 antibody,Abcam,AB84027

Host

Rabbit

Reactivity

Human

Application

sELISA, WB

Conjugate

Biotin

Platform ID

BAB039991353

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-FGF2 antibody
Cat. No.AB84027
HostRabbit
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationsELISA, WB
ClonalityPolyclonal
ImmunogenRecombinant Full Length Protein corresponding to Human FGF2.
PurityAffinity purification Immunogen
Appearance/FormLyophilized
ShippingBlue Ice
FormulationConstituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed : 8663044). Also acts as an integrin ligand which is required for FGF2 signaling (PubMed : 28302677). Binds to integrin ITGAV : ITGB3 (PubMed : 28302677). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (PubMed : 28302677, PubMed : 8663044). Functions as a potent mitogen in vitro (PubMed : 1721615, PubMed : 3732516, PubMed : 3964259). Can induce angiogenesis (PubMed : 23469107, PubMed : 28302677). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (PubMed : 29501879). See full target information FGF2

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