Biotin Anti-SARS-CoV-2 envelope protein antibody,Abcam,AB284658

Host

Rabbit

Reactivity

SARS-CoV-2

Application

ELISA

Conjugate

Biotin

Platform ID

BAB166952911

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-SARS-CoV-2 envelope protein antibody
Cat. No.AB284658
HostRabbit
ReactivitySARS-CoV-2
ConjugationBiotin
ApplicationELISA
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
Appearance/FormLiquid
ShippingAmbient - Can Ship with Ice
FormulationPreservative: 0.02% Sodium azide Constituents: 99.9698% Water, 0.00016% Sodium chloride, 0.00003% disodium hydrogen phosphate, 0.00001% Potassium chloride, 0.00001% Sodium dihydrogen phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis (By similarity). Regulates the localization of S protein at cis-Golgi, the place of virus budding (PubMed : 33229438). May act by slowing down the cell secretory pathway (PubMed : 33229438). May interfere with tight-junction stability by interacting with host MPP5. This would result in disruption of epithelial barriers, thereby amplifying inflammatory processes (PubMed : 32891874). See full target information E

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