Biotin Anti-Tissue Plasminogen Activator antibody,Abcam,AB51518

Host

Sheep

Reactivity

Human

Application

IP, WB, ELISA

Conjugate

Biotin

Platform ID

BAB667202791

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameBiotin Anti-Tissue Plasminogen Activator antibody
Cat. No.AB51518
HostSheep
IsotypeIgG
ReactivityHuman
ConjugationBiotin
ApplicationIP, WB, ELISA
ClonalityPolyclonal
Concentration0.43 mg/mL Batch dependent concentration
ImmunogenNative Full Length Protein corresponding to Human PLAT.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.25% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. During oocyte activation, plays a role in cortical granule reaction in the zona reaction, which contributes to the block to polyspermy (By similarity). See full target information PLAT

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